MRPS2

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. [provided by RefSeq, Jul 2008]

Description

mitochondrial ribosomal protein S2

Protein family

Ribosomal proteins

Chromosome

9:q34.3 (138391830 - 138396519)

Ensembl ID

ENSG00000122140  (ver. 69.37)

Orthologs

Mouse Mrps2: ENSMUSG00000035772

Human splice variants
Mouse splice variants