CA3

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]

Description

carbonic anhydrase III, muscle specific

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Plasma proteins

Chromosome

8:q21.2 (86285665 - 86361269)

Ensembl ID

ENSG00000164879  (ver. 71.37)

Orthologs

Mouse Car3: ENSMUSG00000027559

Human splice variants
Mouse splice variants