STK39

This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]

Description

serine threonine kinase 39

Protein family

Enzymes, Kinases

Chromosome

2:q24.3 (168810530 - 169104651)

Ensembl ID

ENSG00000198648  (ver. 69.37)

Orthologs

Mouse Stk39: ENSMUSG00000027030

Human splice variants
Mouse splice variants