AGXT

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]

Description

alanine-glyoxylate aminotransferase

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins

Chromosome

2:q37.3 (241807896 - 241819919)

Ensembl ID

ENSG00000172482  (ver. 71.37)

Orthologs

Mouse Agxt: ENSMUSG00000026272

Human splice variants
Mouse splice variants