DYRK3

This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Description

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

Protein family

Enzymes, Kinases

Chromosome

1:q32.1 (206808881 - 206857764)

Ensembl ID

ENSG00000143479  (ver. 69.37)

Orthologs

Mouse Dyrk3: ENSMUSG00000016526

Human splice variants
Mouse splice variants