CLK1

This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Description

CDC-like kinase 1

Protein family

Enzymes, Kinases, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins

Chromosome

2:q33.1 (201717732 - 201729422)

Ensembl ID

ENSG00000013441  (ver. 71.37)

Orthologs

Mouse Clk1: ENSMUSG00000026034

Human splice variants
Mouse splice variants