KCND1

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle. [provided by RefSeq, Jul 2008]

Description

potassium voltage-gated channel, Shal-related subfamily, member 1

Protein family

Membrane proteins predicted by MDM, Secreted proteins predicted by MDSP, Voltage-gated ion channels

Chromosome

X:p11.23 (48818639 - 48827976)

Ensembl ID

ENSG00000102057  (ver. 69.37)

Orthologs

Mouse Kcnd1: ENSMUSG00000009731

Human splice variants
Mouse splice variants