SLC16A3

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]). [supplied by OMIM, Mar 2008]

Description

solute carrier family 16, member 3 (monocarboxylic acid transporter 4)

Protein family

Membrane proteins predicted by MDM, Transporters

Chromosome

17:q25.3 (80186273 - 80219005)

Ensembl ID

ENSG00000141526  (ver. 69.37)

Orthologs

Mouse Slc16a3: ENSMUSG00000025161

Human splice variants
Mouse splice variants