ATP1B4

This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Description

ATPase, Na+/K+ transporting, beta 4 polypeptide

Protein family

Membrane proteins predicted by MDM

Chromosome

X:q24 (119495967 - 119516226)

Ensembl ID

ENSG00000101892  (ver. 69.37)

Orthologs

Mouse Atp1b4: ENSMUSG00000016327

Human splice variants
Mouse splice variants