ATIC
gene productAICARFT, IMPCHASE, PURH
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
Featured antibodies
Thermo Fisher Scientific Pierce |
PA5-25928 | 0 references | Polyclonal |
WB ![]() IF ![]() FC
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