CDKL5

This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Description

cyclin-dependent kinase-like 5

Protein family

Enzymes, Kinases, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins

Chromosome

X:p22.13 (18443703 - 18671749)

Ensembl ID

ENSG00000008086  (ver. 71.37)

Orthologs

Mouse Cdkl5: ENSMUSG00000031292

Human splice variants
Mouse splice variants