FLVCR2

This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]

Description

feline leukemia virus subgroup C cellular receptor family, member 2

Protein family

Membrane proteins predicted by MDM, Transporters

Chromosome

14:q24.3 (76044960 - 76129557)

Ensembl ID

ENSG00000119686  (ver. 69.37)

Orthologs

Mouse Mfsd7c: ENSMUSG00000034258

Human splice variants
Mouse splice variants