GPR112

This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010]

Description

G protein-coupled receptor 112

Protein family

GPCRs excl olfactory receptors, Membrane proteins predicted by MDM

Chromosome

X:q26.3 (135383122 - 135519215)

Ensembl ID

ENSG00000156920  (ver. 69.37)

Orthologs

-

Human splice variants