ACOX3

Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008]

Description

acyl-CoA oxidase 3, pristanoyl

Protein family

Enzymes

Chromosome

4:p16.1 (8368439 - 8442450)

Ensembl ID

ENSG00000087008  (ver. 69.37)

Orthologs

Mouse Acox3: ENSMUSG00000029098

Human splice variants
Mouse splice variants