APH1B

gene product

APH-1B, DKFZp564D0372, PSFL

This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]

Ensembl	UniProt	RefSeq	Entrez
ENST00000261879 ENSP00000261879	APH1B_HUMAN Q8WW43 H0YKZ9	NP_112591.2 NP_112591	APH1B 83464
ENST00000380340 ENSP00000369697	Q4R1J8		APH1B 83464
ENST00000380343 ENSP00000369700	APH1B_HUMAN Q8WW43	NP_001139118.1 NP_001139118	APH1B 83464
ENST00000559971 ENSP00000453516			APH1B 83464
ENST00000560353 ENSP00000453327	H0YLT0		APH1B 83464
ENST00000560890 ENSP00000453002	H0YKZ9		APH1B 83464

More gene data

Antibodies

Supportive data in Antibodypedia

Data presented on provider website

Data in Antibodypedia (inconclusive)

Recommended by provider

3 antibodies from 3 providers.

Show Additional Columns

	Antibody	Type
Novus Biologicals 1 antibody
	NBP1-98414	Polyclonal
Aviva Systems Biology 1 antibody
	ARP53808_P050	Polyclonal
EMD Millipore 1 antibody
	06-1029	Polyclonal

APH1B

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