KCNB2

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells. [provided by RefSeq, Jul 2008]

Description

potassium voltage-gated channel, Shab-related subfamily, member 2

Protein family

Membrane proteins predicted by MDM, Voltage-gated ion channels

Chromosome

8:q13.3 (73449626 - 73850584)

Ensembl ID

ENSG00000182674  (ver. 69.37)

Orthologs

Mouse Kcnb2: ENSMUSG00000092083

Human splice variants
Mouse splice variants