PRKX

This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y. [provided by RefSeq, Feb 2010]

Description

protein kinase, X-linked

Protein family

Enzymes, Kinases

Chromosome

X:p22.33 (3522411 - 3631649)

Ensembl ID

ENSG00000183943  (ver. 69.37)

Orthologs

Mouse Prkx: ENSMUSG00000035725

Human splice variants
Mouse splice variants