APOL1

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Description

apolipoprotein L, 1

Protein family

Membrane proteins predicted by MDM, Secreted proteins predicted by MDSP

Chromosome

22:q12.3 (36649056 - 36663576)

Ensembl ID

ENSG00000100342  (ver. 69.37)

Orthologs

-

Human splice variants