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- Antigen structure
- References [71]
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- Product number
- 11313-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11313-2-AP, RRID:AB_2223815
- Product name
- Alpha Actinin antibody
- Antibody type
- Polyclonal
- Description
- Alpha Actinin antibody (Cat. #11313-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Shear-Induced Anisotropic Supramolecular Gel Noodles for Improved Cell Guidance in Polarized Tissue Engineering.
Molecular tension indicators reveal unexpectedly complex regulation of tension in live mouse organs.
The Ets2 super-enhancer modulates endothelial-mesenchymal transition during cardiac ageing.
The combination of paeoniflorin and hydroxysafflor yellow A alleviated pulmonary thrombosis by inhibiting platelet-neutrophil interaction via the P-selectin-PSGL-1 signaling axis.
LncRNA Foxo6os as a Novel " Scaffold" Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure.
ANXA4 Alleviates Cardiomyocyte Injury Associated With Ischemia-Reperfusion by Interfering With NFκB p50's Transcriptional Activation of RAGE.
IL6/STAT3 induced GRWD1 mediates aerobic glycolysis via P53/GLUT1 signal axis in colon carcinoma.
METTL3-mediated m6A modification of FUNDC1/IP3R2 pathway facilitates cardiac hypertrophy in obesity hypertension.
Actin-myosin complex dissociation initiates programmed cell death during cold storage of grass carp muscle.
Antimicrobial peptide CRAMP/LL-37 mediates ferroptosis resistance in cardiomyocytes by inhibiting cathepsin L.
Assessing cardiac insufficiency risks of aflatoxin B1 through network toxicology and molecular docking analyses.
TDP-43 skein-like inclusions are formed by BAG3- and HSP70-guided co-aggregation with actin-binding proteins.
STN1 Shields CTC1 From TRIM32-Mediated Ubiquitination to Prevent Cellular Aging.
Impact of residual feed intake on jejunal tight junction morphology and gene expression in slow-growing Korat chickens.
Rab32 protects mitochondrial function by anchoring Fancd2 and mediates the protective effect of penehyclidine hydrochloride against myocardial ischemia-reperfusion injury.
Tenotomized Achilles tendons of MRL/MpJ mice show scar-mediated healing, but have superior recovery of biomechanical properties.
Serinc2 antagonizes pressure overload-induced cardiac hypertrophy via regulating the amino acid/mTORC1 signaling pathway.
Medium from human iPSC-derived primitive macrophages promotes adult cardiomyocyte proliferation and cardiac regeneration.
ERBB4 as a therapeutic target in aortic dissection: Implications for cell-based therapies in vascular regeneration.
Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia-Reperfusion Injury.
Inhibition of Piezo1 ameliorates septic cardiomyopathy by blocking calcium-dependent PANoptosis.
A Langendorff-heart discovery pipeline demonstrates cardiomyocyte targeting by extracellular vesicles functionalized with beta-blockers using click-chemistry.
Constitutive Hepatic mTORC1 Activation Aggravates Alcohol-Induced Liver Injury via Endoplasmic Reticulum Stress-Mediated Ferroptosis.
Nicotinamide riboside promoted cardiac energetics and alleviated doxorubicin-induced cardiotoxicity via SIRT1/ERRα signal in human pluripotent stem cells-derived cardiomyocytes.
Gremlin1 repression-mediated mitochondrial network hyperfunction contributes to TCE-induced zebrafish cardiac defects.
The transcription factor CREB regulates epithelial-mesenchymal transition of lens epithelial cells by phosphorylation-dependent and phosphorylation-independent mechanisms.
Small-molecule activator of SMUG1 enhances repair of pyrimidine lesions in DNA.
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m(6)A methylation: a novel mechanism early during radiation-induced liver injury.
Emerging of Ultrafine Membraneless Organelles as the Missing Piece of Nanostress: Mechanism of Biogenesis and Implications at Multilevels.
LRRc17-RANKL pathway regulates mitophagy and contributes to atrial remodeling in diabetes.
Proteasome-activating peptide 1 attenuates cardiac ischaemia/reperfusion-induced ferroptosis through the β5i-p53-SLC7A11 axis.
Improved Cell Adhesion on Self-Assembled Chiral Nematic Cellulose Nanocrystal Films.
Hsa-miR-7974 Suppresses Epstein-Barr Virus Reactivation by Directly Targeting BZLF1 and BRLF1.
Hypoxia reconstructed colorectal tumor microenvironment weakening anti-tumor immunity: construction of a new prognosis predicting model through transcriptome analysis.
An enzyme-mimicking reactive oxygen species scavenger targeting oxidative stress-inflammation cycle ameliorates IR-AKI by inhibiting pyruvate dehydrogenase kinase 4.
The mechanosensitive Piezo1 channel exacerbates myocardial ischaemia/reperfusion injury by activating caspase-8-mediated PANoptosis.
Role of KLF4 and SIAT7A interaction accelerates myocardial hypertrophy induced by Ang II.
CBR-470-1 protects against cardiomyocyte death in ischaemia/reperfusion injury by activating the Nrf2-GPX4 cascade.
Increased Secreted Frizzled-Related Protein 2 in Hypertension-Induced Left Ventricular Remodeling.
CRISPR-Cas9-mediated deletion of carbonic anhydrase 2 in the ciliary body to treat glaucoma.
Enhancing myocardial infarction treatment through bionic hydrogel-mediated spatial combination therapy via mtDNA-STING crosstalk modulation.
PKD knockdown mitigates Ang II-induced cardiac hypertrophy and ferroptosis via the JNK/P53 signaling pathway.
N-arachidonoylphenolamine alleviates ischaemia/reperfusion-induced cardiomyocyte necroptosis by restoring proteasomal activity.
Paxillin phase separation promotes focal adhesion assembly and integrin signaling.
DPY30 Promotes Proliferation and Cell Cycle Progression of Colorectal Cancer Cells via Mediating H3K4 Trimethylation.
Ganoderma lucidum polysaccharides attenuates pressure-overload-induced pathological cardiac hypertrophy.
SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells.
Modification of lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression.
MK-886 protects against cardiac ischaemia/reperfusion injury by activating proteasome-Keap1-NRF2 signalling.
Homology-directed repair of an MYBPC3 gene mutation in a rat model of hypertrophic cardiomyopathy.
Guanxinning injection ameliorates cardiac remodeling in HF mouse and 3D heart spheroid models via p38/FOS/MMP1-mediated inhibition of myocardial hypertrophy and fibrosis.
Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection.
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Retinoic Acid Receptor Gamma (RARγ) Promotes Cartilage Destruction through Positive Feedback Activation of NF-κB Pathway in Human Osteoarthritis.
Identification and validation of an immune signature associated with EMT and metabolic reprogramming for predicting prognosis and drug response in bladder cancer.
Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration.
A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.
CYP27A1 inhibits proliferation and migration of clear cell renal cell carcinoma via activation of LXRs/ABCA1.
MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes.
Calponin 1 contributes to myofibroblast differentiation of human pleural mesothelial cells.
CaMKII and Kalirin, a Rac1-GEF, regulate Akt phosphorylation involved in contraction-induced glucose uptake in skeletal muscle cells.
A novel small compound TOIDC suppresses lipogenesis via SREBP1-dependent signaling to curb MAFLD.
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
Adipocyte-specific deletion of Depdc5 exacerbates insulin resistance and adipose tissue inflammation in mice.
Disparate effects of MMP and TIMP modulation on coronary atherosclerosis and associated myocardial fibrosis.
Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance.
Dynamic spatiotemporal expression pattern of limbal stem cell putative biomarkers during mouse development.
miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury.
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
Ghosh D, Walker M, Matthews L, Patterson C, Dobre O, Vassalli M, Adams DJ
Small (Weinheim an der Bergstrasse, Germany) 2026 May;22(26):e13952
Small (Weinheim an der Bergstrasse, Germany) 2026 May;22(26):e13952
Molecular tension indicators reveal unexpectedly complex regulation of tension in live mouse organs.
Fujiwara K, Fujiki K, Akama TO, Shirahige K, Shiojima I, Nakamura T, Hirai M
Communications biology 2026 Feb 19;9(1)
Communications biology 2026 Feb 19;9(1)
The Ets2 super-enhancer modulates endothelial-mesenchymal transition during cardiac ageing.
Guo Z, Li L, Luo J, Xue W, Bian S, Zhu Y, Huo D, Yang W, Ma J, Hao Y, Fan G, Hao B, Liao S
Cardiovascular research 2026 Feb 14;121(18):2892-2908
Cardiovascular research 2026 Feb 14;121(18):2892-2908
The combination of paeoniflorin and hydroxysafflor yellow A alleviated pulmonary thrombosis by inhibiting platelet-neutrophil interaction via the P-selectin-PSGL-1 signaling axis.
Shang T, Zhang Y, Pan T, Shen R, Chang J, Zhang ZS, Feng Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157995
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157995
LncRNA Foxo6os as a Novel " Scaffold" Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure.
Sheng J, Lin Q, Sun Y, Meng Y, Hu S, Cao H, Lin F, Zhu Y, Peng L, Li L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e07365
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e07365
ANXA4 Alleviates Cardiomyocyte Injury Associated With Ischemia-Reperfusion by Interfering With NFκB p50's Transcriptional Activation of RAGE.
Zhao Z, Zhao Y, Zang X, Ren Y, Song W, Wang L, Chen K, Liang E, Zhou Y, Wang X, Niu K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71033
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71033
IL6/STAT3 induced GRWD1 mediates aerobic glycolysis via P53/GLUT1 signal axis in colon carcinoma.
Shang J, Ren HY, Liu FH, Liu DH, Tang SH, Guan GX, Su GQ, Shen DY, Zhou X
Scientific reports 2025 Sep 29;15(1):33534
Scientific reports 2025 Sep 29;15(1):33534
METTL3-mediated m6A modification of FUNDC1/IP3R2 pathway facilitates cardiac hypertrophy in obesity hypertension.
Ma Y, Li D, Zhou X, Chen X, Hou C, Li Y, Zhao Y, Gui M, Yao L, Li J, Wang M, Fu D, Lu B
Life sciences 2025 Sep 15;377:123780
Life sciences 2025 Sep 15;377:123780
Actin-myosin complex dissociation initiates programmed cell death during cold storage of grass carp muscle.
Xiong X, Zhang H, Chen L, Dou P, Huang T, Zhuang S, Tan Y, Ma H, Hong H, Luo Y
Food research international (Ottawa, Ont.) 2025 Oct;217:116744
Food research international (Ottawa, Ont.) 2025 Oct;217:116744
Antimicrobial peptide CRAMP/LL-37 mediates ferroptosis resistance in cardiomyocytes by inhibiting cathepsin L.
Liu Z, Zhang Q, Su D, Chen H, Wang B, Ye L, Wang P, Wu J, Jia W, Liu L, Wang J, Miao S
Basic research in cardiology 2025 Oct;120(5):1011-1025
Basic research in cardiology 2025 Oct;120(5):1011-1025
Assessing cardiac insufficiency risks of aflatoxin B1 through network toxicology and molecular docking analyses.
Zhang Q, Zhang Q, Jiang P, Zhao X, Wen Z, Liu Y, Cao Q, Wang S
Ecotoxicology and environmental safety 2025 Oct 1;304:119095
Ecotoxicology and environmental safety 2025 Oct 1;304:119095
TDP-43 skein-like inclusions are formed by BAG3- and HSP70-guided co-aggregation with actin-binding proteins.
Lu S, Zhang S, Oung S, Diedrich JK, Han P, Arnold-Garcia O, Ohkubo T, Arogundade OA, Vazquez-Sanchez S, Zhang K, Ravits J, Yates Iii JR, Cleveland DW
Nature cell biology 2025 Nov;27(11):1925-1937
Nature cell biology 2025 Nov;27(11):1925-1937
STN1 Shields CTC1 From TRIM32-Mediated Ubiquitination to Prevent Cellular Aging.
Lan Y, Liang X, Kuang G, Ma T, Zhang F, Huang Z, Wang H, Luo Z, Feng X
Aging cell 2025 Nov;24(11):e70214
Aging cell 2025 Nov;24(11):e70214
Impact of residual feed intake on jejunal tight junction morphology and gene expression in slow-growing Korat chickens.
Kongthungmon S, Pengsanthia S, Kamkrathok B, Kaewsatuan P, Molee W, Molee A
Poultry science 2025 Nov;104(11):105667
Poultry science 2025 Nov;104(11):105667
Rab32 protects mitochondrial function by anchoring Fancd2 and mediates the protective effect of penehyclidine hydrochloride against myocardial ischemia-reperfusion injury.
Zhang K, Yang K, Zeng L, Xiao Y, Yu J
International immunopharmacology 2025 May 27;156:114697
International immunopharmacology 2025 May 27;156:114697
Tenotomized Achilles tendons of MRL/MpJ mice show scar-mediated healing, but have superior recovery of biomechanical properties.
Tang N, Wilson K, Weldemariam MM, Tian H, Hart CD, Ramnath P, Sivalingam DS, Glazier J, Jiang J, Leong N, Lowe T, Kane MA, Iwamoto M, Kuo CK, Enomoto-Iwamoto M
bioRxiv : the preprint server for biology 2025 May 16;
bioRxiv : the preprint server for biology 2025 May 16;
Serinc2 antagonizes pressure overload-induced cardiac hypertrophy via regulating the amino acid/mTORC1 signaling pathway.
Mao S, Yang M, Liu H, Wang S, Liu M, Hu S, Liu B, Ju H, Liu Z, Huang M, He S, Cheng M, Wu G
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167650
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167650
Medium from human iPSC-derived primitive macrophages promotes adult cardiomyocyte proliferation and cardiac regeneration.
Xiao Y, Zhang H, Liu X, Xu P, Du H, Wang J, Shen J, Li Y, Wang Y, He C, Feng H, Liu J, Zhou Y, Liu S, Gao Z, Zang J, Bi J, Tang TS, Gu Q, Wei T, Wang J, Song M
Nature communications 2025 Mar 27;16(1):3012
Nature communications 2025 Mar 27;16(1):3012
ERBB4 as a therapeutic target in aortic dissection: Implications for cell-based therapies in vascular regeneration.
Shi Y, Meng J, Zhang S, Yang S, Liu G, Wu Z, Shen C, Shi C
Biomolecules & biomedicine 2025 Mar 14;25(10):2324-2334
Biomolecules & biomedicine 2025 Mar 14;25(10):2324-2334
Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia-Reperfusion Injury.
Cheng N, Luo Q, Yang Y, Shao N, Nie T, Deng X, Chen J, Zhang S, Huang Y, Hu K, Luo L, Xiao Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(24):e2410590
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(24):e2410590
Inhibition of Piezo1 ameliorates septic cardiomyopathy by blocking calcium-dependent PANoptosis.
Zhang YT, Li HH, Teng F
European journal of pharmacology 2025 Jun 5;996:177438
European journal of pharmacology 2025 Jun 5;996:177438
A Langendorff-heart discovery pipeline demonstrates cardiomyocyte targeting by extracellular vesicles functionalized with beta-blockers using click-chemistry.
Park KC, Jaafari AM, Smith CA, Lobo AR, Errichelli L, Şimşek G, Gunadasa-Rohling M, Marchant A, Levitin MO, Castilla-Llorente V, Vilela P, Swietach P
Journal of molecular and cellular cardiology 2025 Jul;204:89-100
Journal of molecular and cellular cardiology 2025 Jul;204:89-100
Constitutive Hepatic mTORC1 Activation Aggravates Alcohol-Induced Liver Injury via Endoplasmic Reticulum Stress-Mediated Ferroptosis.
Xu L, Zhao Y, Yang Y, Qi E, Liu B, Zhuang P, Song S, Chang T, Chen Z, Kang X, Xiong X
The American journal of pathology 2025 Jul;195(7):1209-1222
The American journal of pathology 2025 Jul;195(7):1209-1222
Nicotinamide riboside promoted cardiac energetics and alleviated doxorubicin-induced cardiotoxicity via SIRT1/ERRα signal in human pluripotent stem cells-derived cardiomyocytes.
Wang R, Zhang H, Yi Q, Wang YP, Xu H, Tan B, Zhu J
Life sciences 2025 Jul 15;373:123685
Life sciences 2025 Jul 15;373:123685
Gremlin1 repression-mediated mitochondrial network hyperfunction contributes to TCE-induced zebrafish cardiac defects.
Deng H, Bai Z, Huangfu C, Wang N, Chen M, Li G, Huang C, Ao T, Tang X, Xia T, Zhang L, Shen P, Zhou W, Gao Y
Cell communication and signaling : CCS 2025 Jul 1;23(1):318
Cell communication and signaling : CCS 2025 Jul 1;23(1):318
The transcription factor CREB regulates epithelial-mesenchymal transition of lens epithelial cells by phosphorylation-dependent and phosphorylation-independent mechanisms.
Zhang L, Wang JM, Wang L, Zheng S, Bai Y, Fu JL, Wang Y, Zhang JP, Xiao Y, Hou M, Nie Q, Gan YW, Liang XM, Hu XB, Li DW
The Journal of biological chemistry 2025 Jan;301(1):108064
The Journal of biological chemistry 2025 Jan;301(1):108064
Small-molecule activator of SMUG1 enhances repair of pyrimidine lesions in DNA.
Gao Y, McPherson L, Adimoolam S, Suresh S, Wilson DL, Das I, Park ER, Ng CSC, Jun YW, Ford JM, Kool ET
DNA repair 2025 Feb;146:103809
DNA repair 2025 Feb;146:103809
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m(6)A methylation: a novel mechanism early during radiation-induced liver injury.
Song GY, Yu QH, Xing XK, Fan XM, Xu SG, Zhang WB, Wu YY, Zhang N, Chao TZ, Wang F, Ding CS, Guo CY, Ma L, Sun CY, Duan SY, Xu P
Cell death & disease 2025 Feb 24;16(1):127
Cell death & disease 2025 Feb 24;16(1):127
Emerging of Ultrafine Membraneless Organelles as the Missing Piece of Nanostress: Mechanism of Biogenesis and Implications at Multilevels.
Liu J, Zheng L, Li X, Tang W, Guo M, Wang Y, Tan X, Chang J, Zhao H, Zhu D, Ma YQ, Huo D
ACS nano 2025 Feb 11;19(5):5659-5679
ACS nano 2025 Feb 11;19(5):5659-5679
LRRc17-RANKL pathway regulates mitophagy and contributes to atrial remodeling in diabetes.
Zhou L, Liu D, Bao Q, Zhou Z, Jia Z, Gao X, Song W, Tse G, Lip GYH, Liu T, Shao Q
Cellular signalling 2025 Dec;136:112148
Cellular signalling 2025 Dec;136:112148
Proteasome-activating peptide 1 attenuates cardiac ischaemia/reperfusion-induced ferroptosis through the β5i-p53-SLC7A11 axis.
Shi KN, Li PB, Jiang WX, Li HH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Aug;189:118296
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Aug;189:118296
Improved Cell Adhesion on Self-Assembled Chiral Nematic Cellulose Nanocrystal Films.
Wang X, Xu H, Ning F, Duan S, Hu Y, Ding X, Xu FJ
Macromolecular rapid communications 2025 Apr;46(7):e2400339
Macromolecular rapid communications 2025 Apr;46(7):e2400339
Hsa-miR-7974 Suppresses Epstein-Barr Virus Reactivation by Directly Targeting BZLF1 and BRLF1.
Li H, Wang H, Wang J, Lu X, Zhang J, Wang M, Yu D, Li Y, Wang S
Viruses 2025 Apr 23;17(5)
Viruses 2025 Apr 23;17(5)
Hypoxia reconstructed colorectal tumor microenvironment weakening anti-tumor immunity: construction of a new prognosis predicting model through transcriptome analysis.
Zhang R, Gao Y, Li C, Tao R, Mao G, Song T, Nie W, Liu S, Tao K, Li W
Frontiers in immunology 2024;15:1425687
Frontiers in immunology 2024;15:1425687
An enzyme-mimicking reactive oxygen species scavenger targeting oxidative stress-inflammation cycle ameliorates IR-AKI by inhibiting pyruvate dehydrogenase kinase 4.
He W, Ding C, Lin T, Wang B, Wang W, Deng Z, Jin T, Shang Y, Zheng D, Bai T, Zhang M, Li R, Jin J, He Q
Theranostics 2024;14(19):7534-7553
Theranostics 2024;14(19):7534-7553
The mechanosensitive Piezo1 channel exacerbates myocardial ischaemia/reperfusion injury by activating caspase-8-mediated PANoptosis.
Li PB, Bai JQ, Jiang WX, Li HH, Li CM
International immunopharmacology 2024 Sep 30;139:112664
International immunopharmacology 2024 Sep 30;139:112664
Role of KLF4 and SIAT7A interaction accelerates myocardial hypertrophy induced by Ang II.
Yao Q, Hu X, Bian T, Zhang Q, Xue Z, Lv Y, Ren S, Chen Y, Zhang D, Chen L
Journal of cellular and molecular medicine 2024 Oct;28(20):e70144
Journal of cellular and molecular medicine 2024 Oct;28(20):e70144
CBR-470-1 protects against cardiomyocyte death in ischaemia/reperfusion injury by activating the Nrf2-GPX4 cascade.
Qiu ZY, Shi KN, Li HH, Zhang B
Toxicology and applied pharmacology 2024 Nov;492:117113
Toxicology and applied pharmacology 2024 Nov;492:117113
Increased Secreted Frizzled-Related Protein 2 in Hypertension-Induced Left Ventricular Remodeling.
Cao M, Jiang X, Wang X, Gao P, Zou Y
Reviews in cardiovascular medicine 2024 May;25(5):171
Reviews in cardiovascular medicine 2024 May;25(5):171
CRISPR-Cas9-mediated deletion of carbonic anhydrase 2 in the ciliary body to treat glaucoma.
Jiang J, Kong K, Fang X, Wang D, Zhang Y, Wang P, Yang Z, Zhang Y, Liu X, Aung T, Li F, Yu-Wai-Man P, Zhang X
Cell reports. Medicine 2024 May 21;5(5):101524
Cell reports. Medicine 2024 May 21;5(5):101524
Enhancing myocardial infarction treatment through bionic hydrogel-mediated spatial combination therapy via mtDNA-STING crosstalk modulation.
Zheng Z, Sun J, Wang J, He S, Liu Z, Xie J, Yu CY, Wei H
Journal of controlled release : official journal of the Controlled Release Society 2024 Jul;371:570-587
Journal of controlled release : official journal of the Controlled Release Society 2024 Jul;371:570-587
PKD knockdown mitigates Ang II-induced cardiac hypertrophy and ferroptosis via the JNK/P53 signaling pathway.
Lv C, Zhou L, Meng Y, Yuan H, Geng J
Cellular signalling 2024 Jan;113:110974
Cellular signalling 2024 Jan;113:110974
N-arachidonoylphenolamine alleviates ischaemia/reperfusion-induced cardiomyocyte necroptosis by restoring proteasomal activity.
Bai JQ, Li PB, Li CM, Li HH
European journal of pharmacology 2024 Jan 15;963:176235
European journal of pharmacology 2024 Jan 15;963:176235
Paxillin phase separation promotes focal adhesion assembly and integrin signaling.
Liang P, Wu Y, Zheng S, Zhang J, Yang S, Wang J, Ma S, Zhang M, Gu Z, Liu Q, Jiang W, Xing Q, Wang B
The Journal of cell biology 2024 Apr 1;223(4)
The Journal of cell biology 2024 Apr 1;223(4)
DPY30 Promotes Proliferation and Cell Cycle Progression of Colorectal Cancer Cells via Mediating H3K4 Trimethylation.
Su WC, Mao XM, Li SY, Luo CY, Fan R, Jiang HF, Zhang LJ, Wang YT, Su GQ, Shen DY
International journal of medical sciences 2023;20(7):901-917
International journal of medical sciences 2023;20(7):901-917
Ganoderma lucidum polysaccharides attenuates pressure-overload-induced pathological cardiac hypertrophy.
Zhen C, Wu X, Zhang J, Liu D, Li G, Yan Y, He X, Miao J, Song H, Yan Y, Zhang Y
Frontiers in pharmacology 2023;14:1127123
Frontiers in pharmacology 2023;14:1127123
SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells.
Wang Y, Wang JM, Xiao Y, Hu XB, Zheng SY, Fu JL, Zhang L, Gan YW, Liang XM, Li DW
Aging 2023 Sep 7;15(17):8812-8832
Aging 2023 Sep 7;15(17):8812-8832
Modification of lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression.
Zhang Z, Wang Y, Liang Z, Meng Z, Zhang X, Ma G, Chen Y, Zhang M, Su Y, Li Z, Liang Y, Niu H
iScience 2023 Nov 17;26(11):108142
iScience 2023 Nov 17;26(11):108142
MK-886 protects against cardiac ischaemia/reperfusion injury by activating proteasome-Keap1-NRF2 signalling.
Shi KN, Li PB, Su HX, Gao J, Li HH
Redox biology 2023 Jun;62:102706
Redox biology 2023 Jun;62:102706
Homology-directed repair of an MYBPC3 gene mutation in a rat model of hypertrophic cardiomyopathy.
Nie J, Han Y, Jin Z, Hang W, Shu H, Wen Z, Ni L, Wang DW
Gene therapy 2023 Jun;30(6):520-527
Gene therapy 2023 Jun;30(6):520-527
Guanxinning injection ameliorates cardiac remodeling in HF mouse and 3D heart spheroid models via p38/FOS/MMP1-mediated inhibition of myocardial hypertrophy and fibrosis.
Fan S, Xiao G, Ni J, Zhao Y, Du H, Liang Y, Lv M, He S, Fan G, Zhu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114642
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114642
Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection.
Hu YJ, Song GY, Zhang F, Zhang N, Wang F, Wang JL, Wang X, Wang TY, Li YF, Yan YD, Dou WT, Cheng CY, Xu P
iScience 2023 Feb 17;26(2):105932
iScience 2023 Feb 17;26(2):105932
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Cui L, Lu Y, Zheng J, Guo B, Zhao X
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Retinoic Acid Receptor Gamma (RARγ) Promotes Cartilage Destruction through Positive Feedback Activation of NF-κB Pathway in Human Osteoarthritis.
Yu YW, Li SY, Zhang LJ, Wang QL, Liu ZG, Chen QZ, Song HY, Shen DY, Yan J
Mediators of inflammation 2022;2022:1875736
Mediators of inflammation 2022;2022:1875736
Identification and validation of an immune signature associated with EMT and metabolic reprogramming for predicting prognosis and drug response in bladder cancer.
Zhang Z, Yu Y, Li P, Wang M, Jiao W, Liang Y, Niu H
Frontiers in immunology 2022;13:954616
Frontiers in immunology 2022;13:954616
Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration.
Zou M, Ke Q, Nie Q, Qi R, Zhu X, Liu W, Hu X, Sun Q, Fu JL, Tang X, Liu Y, Li DW, Gong L
Cell death and differentiation 2022 Sep;29(9):1816-1833
Cell death and differentiation 2022 Sep;29(9):1816-1833
A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.
Zheng Z, Lei C, Liu H, Jiang M, Zhou Z, Zhao Y, Yu CY, Wei H
Advanced healthcare materials 2022 Oct;11(19):e2200990
Advanced healthcare materials 2022 Oct;11(19):e2200990
CYP27A1 inhibits proliferation and migration of clear cell renal cell carcinoma via activation of LXRs/ABCA1.
Liang Z, Jiao W, Wang L, Chen Y, Li D, Zhang Z, Zhang Z, Liang Y, Niu H
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Experimental cell research 2022 Oct 1;419(1):113279
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Biochemical and biophysical research communications 2021 Sep 10;569:118-124
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Biochemical and biophysical research communications 2021 Mar 12;544:44-51
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Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2013 Mar;67(2):140-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The alpha Actinin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human alpha Actinin. This antibody recognizes human,mouse,rat antigen. The alpha Actinin antibody has been validated for the following applications: ELISA, WB analysis.
