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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2089 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2089, RRID:AB_1577812
- Product name
- KDR polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of KDR.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling.
p38 MAPK inhibition is critically involved in VEGFR-2-mediated endothelial cell survival.
A set of loop-1 and -3 structures in the novel vascular endothelial growth factor (VEGF) family member, VEGF-ENZ-7, is essential for the activation of VEGFR-2 signaling.
Zeng H, Zhao D, Yang S, Datta K, Mukhopadhyay D
The Journal of biological chemistry 2003 Jun 6;278(23):20738-45
The Journal of biological chemistry 2003 Jun 6;278(23):20738-45
p38 MAPK inhibition is critically involved in VEGFR-2-mediated endothelial cell survival.
Yilmaz A, Kliche S, Mayr-Beyrle U, Fellbrich G, Waltenberger J
Biochemical and biophysical research communications 2003 Jul 4;306(3):730-6
Biochemical and biophysical research communications 2003 Jul 4;306(3):730-6
A set of loop-1 and -3 structures in the novel vascular endothelial growth factor (VEGF) family member, VEGF-ENZ-7, is essential for the activation of VEGFR-2 signaling.
Kiba A, Yabana N, Shibuya M
The Journal of biological chemistry 2003 Apr 11;278(15):13453-61
The Journal of biological chemistry 2003 Apr 11;278(15):13453-61
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of KDR polyclonal antibody (Cat # PAB2089) in HeLa cell lysate. KDR (arrow) was detected using purified Polyclonal antibody.Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with KDR polyclonal antibody (Cat # PAB2089) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
