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KDR
Kinase insert domain receptorCD309, FLK1, VEGFR, VEGFR2
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
Top validated antibodies |
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| Novus Biologicals |  NB200-208 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| ReliaTech GmbH | 101-M32 |
3 references | Monoclonal |
WB
EL
IP
IHC
FC
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| R&D Systems | AF644 |
49 references | Polyclonal |
WB
IHC
FC
BN
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| antibodies-online | ABIN4365109 |
1 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| OriGene | DP3509 |
Polyclonal |
WB
EL
IP
IHC
FC
FA
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