FNab09964

antibody from FineTest Biotech

Targeting: KDR CD309, FLK1, VEGFR, VEGFR2

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ELISA

Immunohistochemistry

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Validation data

Product number: FNab09964 - Provider product page
Provider: FineTest Biotech
Product name: Phospho-VEGF Receptor 2 (Y1175) antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: A phospho specific peptide correspo nding to residues surrounding Y1175 of human VEGF Receptor 2
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

KDR protein structure - FNab09964 shown in red.