PA1-4612

antibody from Invitrogen Antibodies

Targeting: YWHAB YWHAA

Western blot (Data presented on provider website)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

PA1-4612

Provider

Invitrogen Antibodies

Product name

Phospho-14-3-3 beta (Ser58) Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

This antibody is predicted to react with bovine, canine, chicken, mouse, non-human primate, sheep, Xenopus and zebrafish based on 100% sequence homology. This antibody is specific for the ~29 kDa 14-3-3 protein phosphorylated at Ser58. Immunolabeling is blocked by preadsorption of the antibody with the protein used to generate the antibody.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100 μL

Concentration

0.25 mg/mL

Storage

-20°C, Avoid Freeze/Thaw Cycles

References

Submitted references

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation.

Fidalgo M, Fraile M, Pires A, Force T, Pombo C, Zalvide J
Journal of cell science 2010 Apr 15;123(Pt 8):1274-84

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Serine 58 of 14-3-3zeta is a molecular switch regulating ASK1 and oxidant stress-induced cell death.

Zhou J, Shao Z, Kerkela R, Ichijo H, Muslin AJ, Pombo C, Force T
Molecular and cellular biology 2009 Aug;29(15):4167-76