BS8210

antibody from Bioworld Technology, Inc
Targeting: GATD3A C21orf33, D21S2048E, ES1, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI
Provider product page for BS8210
Western blot
Immunohistochemistry

Antibody data

Product number
BS8210 - Provider product page
Provider
Bioworld Technology, Inc
Product name
C21orf33 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human C21orf33.
Description
KNP-I (ES1 protein homolog, protein GT335) is a ubiquitously expressed mitochondrial protein that belongs to the ES1 family of proteins. It is a highly conserved protein with homologs identified in various species. This conserved nature suggests an important biological role for the KNP-I protein. The gene that encodes KNP-I (C21orf33) is located on human chromosome 21 in close proximity to a region (D21S25) associated with many genetic diseases. Down syndrome (DS), caused by an extra copy of chromosome 21, is the most common manifestation of trisomic chromosomes. It is likely that the overproduction of the C21orf33 gene product plays a role in the pathology of DS, while its chromosomal location suggests its likely involvement in D21S25 related diseases. While expressed in most tissue, highest expression of KNP-I is found in heart and muscle.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GATD3A protein structure - BS8210 shown in red.