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Protein structure
PPARGC1A
PPARG coactivator 1 alphaPGC-1alpha, PGC1, PGC1A, PPARGC1
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  NBP1-04676 |
112 references | Polyclonal |
WB
ICC
IP
IHC
FC
ChIP
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| Invitrogen Antibodies | PA5-72948 |
4 references | Polyclonal |
WB
IP
IHC
OA
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| Proteintech Group | 66369-1-Ig |
100 references | Monoclonal |
WB
EL
ICC
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| Everest Biotech | EB07856 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| OriGene | TA326711 |
1 references | Polyclonal |
WB
ICC
IHC
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