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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2218 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2218, RRID:AB_1574434
- Product name
- DNMT3L polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of DNMT3L.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Dnmt3L is a transcriptional repressor that recruits histone deacetylase.
Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths.
The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a.
Deplus R, Brenner C, Burgers WA, Putmans P, Kouzarides T, de Launoit Y, Fuks F
Nucleic acids research 2002 Sep 1;30(17):3831-8
Nucleic acids research 2002 Sep 1;30(17):3831-8
Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths.
Kierszenbaum AL
Molecular reproduction and development 2002 Nov;63(3):269-72
Molecular reproduction and development 2002 Nov;63(3):269-72
The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a.
Chedin F, Lieber MR, Hsieh CL
Proceedings of the National Academy of Sciences of the United States of America 2002 Dec 24;99(26):16916-21
Proceedings of the National Academy of Sciences of the United States of America 2002 Dec 24;99(26):16916-21
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of HL-60 cell lysate with DNMT3L polyclonal antibody (Cat # PAB2218).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the DNMT3L polyclonal antibody (Cat # PAB2218) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
