FNab09448

antibody from FineTest Biotech

Targeting: VPS53 FLJ10979, HCCS1

Western blot

ELISA

Immunoprecipitation

Antibody data

Submit

Validation data

Product number: FNab09448 - Provider product page
Provider: FineTest Biotech
Product name: VPS53 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: vacuolar protein sorting 53 homolog
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

VPS53 protein structure - FNab09448 shown in red.