Antibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 11217-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11217-1-AP, RRID:AB_2224626
- Product name
- ALDOA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ALDOA antibody (Cat. #11217-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Aldolase A Enhances Intrahepatic Cholangiocarcinoma Proliferation and Invasion through Promoting Glycolysis.
Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.
Itaconate regulates the glycolysis/pentose phosphate pathway transition to maintain boar sperm linear motility by regulating redox homeostasis.
Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis.
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines.
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress.
C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway.
Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer.
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Characterization of GALNTL5 gene sequence and expression in ovine testes and sperm.
Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Alteration of sperm protein profile induced by cigarette smoking.
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Identification and validation of mouse sperm proteins correlated with epididymal maturation.
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Antipsychotic treatment alters protein expression associated with presynaptic function and nervous system development in rat frontal cortex.
Li X, Yu C, Luo Y, Lin J, Wang F, Sun X, Gao Y, Tan W, Xia Q, Kong X
International journal of biological sciences 2021;17(7):1782-1794
International journal of biological sciences 2021;17(7):1782-1794
Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.
Li X, Zhang Y, Wang X, Lin F, Cheng X, Wang Z, Wang X
Cell biology and toxicology 2021 Sep 12;
Cell biology and toxicology 2021 Sep 12;
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Li R, Li H, Zhu L, Zhang X, Liu D, Li Q, Ni B, Hu L, Zhang Z, Zhang Y, Wang X, Jiang SH
Cell death & disease 2021 Nov 26;12(12):1106
Cell death & disease 2021 Nov 26;12(12):1106
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Wang J, Li Z, Yang X, Qiao Y, Feng C, Yu S, Jing H, Liu W, Ren L, Duan Q, Li XQ, Cao W
Carbohydrate polymers 2021 Mar 1;255:117532
Carbohydrate polymers 2021 Mar 1;255:117532
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Chen X, Li Z, Yong H, Wang W, Wang D, Chu S, Li M, Hou P, Zheng J, Bai J
Cancer letters 2021 Jun 28;508:115-126
Cancer letters 2021 Jun 28;508:115-126
Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.
Li Z, Yang L, Zhang S, Song J, Sun H, Shan C, Wang D, Liu S
Cell transplantation 2021 Jan-Dec;30:9636897211027524
Cell transplantation 2021 Jan-Dec;30:9636897211027524
Itaconate regulates the glycolysis/pentose phosphate pathway transition to maintain boar sperm linear motility by regulating redox homeostasis.
Zhu Z, Umehara T, Tsujita N, Kawai T, Goto M, Cheng B, Zeng W, Shimada M
Free radical biology & medicine 2020 Nov 1;159:44-53
Free radical biology & medicine 2020 Nov 1;159:44-53
Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis.
Wang C, Xu J, Yuan D, Bai Y, Pan Y, Zhang J, Shao C
Molecular and cellular biochemistry 2020 Jun;469(1-2):77-87
Molecular and cellular biochemistry 2020 Jun;469(1-2):77-87
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Ma L, Liu W, Xu A, Ji Q, Ma Y, Tai Y, Wang Y, Shen C, Liu Y, Wang T, Han J, Zhao C
Cancer science 2020 Jun;111(6):2028-2040
Cancer science 2020 Jun;111(6):2028-2040
Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.
Hu J, Chen Z, Bao L, Zhou L, Hou Y, Liu L, Xiong M, Zhang Y, Wang B, Tao Z, Chen K
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jul 8;28(7):1658-1672
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jul 8;28(7):1658-1672
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, Xie F, Zhang S, Shan C
Biochemical pharmacology 2020 Aug;178:114092
Biochemical pharmacology 2020 Aug;178:114092
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines.
Chai Z, Yang Y, Gu Z, Cai X, Ye W, Kong L, Qiu X, Ying L, Wang Z, Wang L
OncoTargets and therapy 2019;12:10415-10425
OncoTargets and therapy 2019;12:10415-10425
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress.
Wang J, Wu Q, Qiu J
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):898-908
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):898-908
C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway.
Zhang C, Zhao LM, Wu H, Tian G, Dai SL, Zhao RY, Shan BE
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(6):2471-2482
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(6):2471-2482
Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer.
Jiang Z, Wang X, Li J, Yang H, Lin X
Journal of cellular and molecular medicine 2018 Sep;22(9):4377-4386
Journal of cellular and molecular medicine 2018 Sep;22(9):4377-4386
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, Li Y, You W, Dong Q, Hong T, Yan Z, Jin S, Wang T, Zhao W, Mai H, Huang J, Han X, Ji Q, Song Q, Yang C, Zhao S, Xu X, Ye Q
Cancer cell 2018 Mar 12;33(3):368-385.e7
Cancer cell 2018 Mar 12;33(3):368-385.e7
Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.
Ma D, Chen X, Zhang PY, Zhang H, Wei LJ, Hu S, Tang JZ, Zhou MT, Xie C, Ou R, Xu Y, Tang KF
Oncogene 2018 Feb 22;37(8):1041-1048
Oncogene 2018 Feb 22;37(8):1041-1048
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Bai D, Li Q, Xiong Y, Wang C, Shen P, Bai L, Yuan L, Wu P
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Characterization of GALNTL5 gene sequence and expression in ovine testes and sperm.
Yao X, Yang H, Zhang Y, Ren C, Nie H, Fan Y, Zhou W, Wang S, Feng X, Wang F
Theriogenology 2017 Jun;95:54-61
Theriogenology 2017 Jun;95:54-61
Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A
Developmental cell 2017 Feb 27;40(4):331-341.e4
Developmental cell 2017 Feb 27;40(4):331-341.e4
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, Wang F, Chi X, Jiang Y, Shao S
PloS one 2016;11(9):e0163622
PloS one 2016;11(9):e0163622
Alteration of sperm protein profile induced by cigarette smoking.
Chen X, Xu W, Miao M, Zhu Z, Dai J, Chen Z, Fang P, Wu J, Nie D, Wang L, Wang Z, Qiao Z, Shi H
Acta biochimica et biophysica Sinica 2015 Jul;47(7):504-15
Acta biochimica et biophysica Sinica 2015 Jul;47(7):504-15
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Liu C, Lin JJ, Yang ZY, Tsai CC, Hsu JL, Wu YJ
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
Identification and validation of mouse sperm proteins correlated with epididymal maturation.
Ijiri TW, Merdiushev T, Cao W, Gerton GL
Proteomics 2011 Oct;11(20):4047-62
Proteomics 2011 Oct;11(20):4047-62
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Lin CC, Chen LC, Tseng VS, Yan JJ, Lai WW, Su WP, Lin CH, Huang CY, Su WC
The European respiratory journal 2011 Jun;37(6):1453-65
The European respiratory journal 2011 Jun;37(6):1453-65
Antipsychotic treatment alters protein expression associated with presynaptic function and nervous system development in rat frontal cortex.
Ma D, Chan MK, Lockstone HE, Pietsch SR, Jones DN, Cilia J, Hill MD, Robbins MJ, Benzel IM, Umrania Y, Guest PC, Levin Y, Maycox PR, Bahn S
Journal of proteome research 2009 Jul;8(7):3284-97
Journal of proteome research 2009 Jul;8(7):3284-97
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11217-1-AP(ALDOA antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using ALDOA antibody 11217-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-ALDOA (IP:11217-1-AP, 3ug; Detection:11217-1-AP 1:1000) with HepG2 cells lysate 6000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 11217-1-AP(ALDOA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 11217-1-AP(ALDOA antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue