Tissue expression
Cell line expression
Protein structure
MVP
Major vault proteinLRP, VAULT1
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Top validated antibodies |
|||||
GeneTex | ![]() |
1 references | Monoclonal |
|
|
Proteintech Group | ![]() |
9 references | Polyclonal |
|
|
Novus Biologicals | ![]() |
2 references | Monoclonal |
|
|
Abnova Corporation | ![]() |
1 references | Monoclonal |
|
|
Invitrogen Antibodies | ![]() |
4 references | Monoclonal |
|