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Protein structure
BIRC3
Baculoviral IAP repeat containing 3API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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| Proteintech Group |  24304-1-AP |
17 references | Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN2846885 |
2 references | Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | NBP1-27972 |
2 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | 24304-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| LSBio | LS-C156821 |
Polyclonal |
WB
ICC
IHC
|
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