BS8130

antibody from Bioworld Technology, Inc
Targeting: TSPAN32 PHEMX, TSSC6
Provider product page for BS8130
Western blot
Immunohistochemistry

Antibody data

Product number
BS8130 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TSPAN32 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TSPAN32.
Description
Phemx (pan-hematopoietic expression protein), also known as PHMX, TSPAN32 (tetraspanin-32) or TSSC6 (tumor-suppressing subtransferable candidate 6), is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin Ï«IIb/Integrin ÉÇ3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate ¡ùoutside-in¡ì signaling. This interaction may be important in the process of wound healing.The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TSPAN32 protein structure - BS8130 shown in red.