BS8183

antibody from Bioworld Technology, Inc
Targeting: PNOC N/OFQ, NOP, PPNOC
Provider product page for BS8183
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8183 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PNOC polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PNOC.
Description
Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids). Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PNOC protein structure - BS8183 shown in red.