600-401-241

antibody from Rockland Immunochemicals, Inc.

Targeting: SPRY2 hSPRY2

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Antibody Data

Product number

600-401-241

Provider

Rockland Immunochemicals, Inc.

Proper citation

Rockland Cat#600-401-241, RRID:AB_2302542

Product name

Anti-Human Sprouty-2 (RABBIT) Antibody - 600-401-241

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Description

Sprouty was originally identified as an inhibitor of Drosophila epidermal growth factor (EGF) and fibroblast growth factor (FGF) receptor signaling during tracheal development. Four isoforms of mammalian sprouty are known (Spry1-Spry4). The role of the mammalian analogs has not been clearly elucidated although it is believed that human Sprouty-2 (hSpry2) may be an inhibitor of cellular migration and proliferation. Spry2 and Spry4 show considerable sequence homology between human and mouse at the C-terminus of the protein. Significant sequence divergence occurs at the N-terminus. Spry2 appears to be abundant in brain, lung and heart tissue, with lesser amounts found in kidney and skeletal muscle. Anti-Human Sprouty-2 (Rabbit) was prepared from monospecific antiserum by immunoaffinity chromatography using hSpry2 protein coupled to agarose beads followed exhaustive dialysis against the buffer stated above.Ê Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Storage

Store vial at -20 deg C prior to opening. Aliquot contents and freeze at -20 deg C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 deg C as an undiluted liquid. Dilute only prior to immediate use.

Handling

Dry Ice