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HYAL1
Hyaluronidase 1HYAL-1, LUCA1
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  NBP1-00201 |
1 references | Polyclonal |
EL
ICC
IHC
FC
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| antibodies-online | ABIN314303 |
1 references | Polyclonal |
EL
ICC
FC
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| Atlas Antibodies | HPA002112 |
2 references | Polyclonal |
IHC
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| Everest Biotech | EB07871 |
Polyclonal |
EL
ICC
IHC
FC
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| Invitrogen Antibodies | PA5-142277 |
Polyclonal |
ICC
IHC
FC
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