Antibody data
- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Western blot [3]
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- Product number
- ABIN151918 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-RECQL2 (ARABIDOPSIS RECQ HELICASE L2), 3'-5' DNA Helicase/ ATP-Dependent Helicase/ Four-Way Junction Helicase/ Protein Binding (RECQL2) (AA 400-450) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 400-450
- Isotype
- IgG
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references DNA2 drives processing and restart of reversed replication forks in human cells.
The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa.
Identification and characterization of SMARCAL1 protein complexes.
Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein.
Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation.
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.
Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1.
Metal-catalyzed oxidation of the Werner syndrome protein causes loss of catalytic activities and impaired protein-protein interactions.
Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, Zellweger R, Moore H, Lee EH, Hendrickson EA, Cejka P, Stewart S, Lopes M, Vindigni A
The Journal of cell biology 2015 Mar 2;208(5):545-62
The Journal of cell biology 2015 Mar 2;208(5):545-62
The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa.
Maddukuri L, Ketkar A, Eddy S, Zafar MK, Eoff RL
Nucleic acids research 2014 Oct 29;42(19):12027-40
Nucleic acids research 2014 Oct 29;42(19):12027-40
Identification and characterization of SMARCAL1 protein complexes.
Bétous R, Glick GG, Zhao R, Cortez D
PloS one 2013;8(5):e63149
PloS one 2013;8(5):e63149
Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein.
Maddukuri L, Ketkar A, Eddy S, Zafar MK, Griffin WC, Eoff RL
The Journal of biological chemistry 2012 Dec 7;287(50):42312-23
The Journal of biological chemistry 2012 Dec 7;287(50):42312-23
Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation.
Thangavel S, Mendoza-Maldonado R, Tissino E, Sidorova JM, Yin J, Wang W, Monnat RJ Jr, Falaschi A, Vindigni A
Molecular and cellular biology 2010 Mar;30(6):1382-96
Molecular and cellular biology 2010 Mar;30(6):1382-96
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.
Rizzo A, Salvati E, Porru M, D'Angelo C, Stevens MF, D'Incalci M, Leonetti C, Gilson E, Zupi G, Biroccio A
Nucleic acids research 2009 Sep;37(16):5353-64
Nucleic acids research 2009 Sep;37(16):5353-64
Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.
Nyunoya T, Monick MM, Klingelhutz AL, Glaser H, Cagley JR, Brown CO, Matsumoto E, Aykin-Burns N, Spitz DR, Oshima J, Hunninghake GW
American journal of respiratory and critical care medicine 2009 Feb 15;179(4):279-87
American journal of respiratory and critical care medicine 2009 Feb 15;179(4):279-87
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1.
Das A, Boldogh I, Lee JW, Harrigan JA, Hegde ML, Piotrowski J, de Souza Pinto N, Ramos W, Greenberg MM, Hazra TK, Mitra S, Bohr VA
The Journal of biological chemistry 2007 Sep 7;282(36):26591-602
The Journal of biological chemistry 2007 Sep 7;282(36):26591-602
Metal-catalyzed oxidation of the Werner syndrome protein causes loss of catalytic activities and impaired protein-protein interactions.
Harrigan JA, Piotrowski J, Di Noto L, Levine RL, Bohr VA
The Journal of biological chemistry 2007 Dec 14;282(50):36403-11
The Journal of biological chemistry 2007 Dec 14;282(50):36403-11
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