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- References [5]
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- Product number
- ABIN453450 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide selected from the C-terminal region of human UCHL1
- Description
- Affinity chromatography on Protein A
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Complex interactions in Parkinson's disease: a two-phased approach.
Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants.
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1).
Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice.
Maraganore DM, de Andrade M, Lesnick TG, Farrer MJ, Bower JH, Hardy JA, Rocca WA
Movement disorders : official journal of the Movement Disorder Society 2003 Jun;18(6):631-6
Movement disorders : official journal of the Movement Disorder Society 2003 Jun;18(6):631-6
Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants.
Nishikawa K, Li H, Kawamura R, Osaka H, Wang YL, Hara Y, Hirokawa T, Manago Y, Amano T, Noda M, Aoki S, Wada K
Biochemical and biophysical research communications 2003 Apr 25;304(1):176-83
Biochemical and biophysical research communications 2003 Apr 25;304(1):176-83
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
Liu Y, Fallon L, Lashuel HA, Liu Z, Lansbury PT Jr
Cell 2002 Oct 18;111(2):209-18
Cell 2002 Oct 18;111(2):209-18
Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1).
Caballero OL, Resto V, Patturajan M, Meerzaman D, Guo MZ, Engles J, Yochem R, Ratovitski E, Sidransky D, Jen J
Oncogene 2002 May 2;21(19):3003-10
Oncogene 2002 May 2;21(19):3003-10
Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice.
Saigoh K, Wang YL, Suh JG, Yamanishi T, Sakai Y, Kiyosawa H, Harada T, Ichihara N, Wakana S, Kikuchi T, Wada K
Nature genetics 1999 Sep;23(1):47-51
Nature genetics 1999 Sep;23(1):47-51
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- (LEFT) Western blot analysis of UCHL1 Antibody (C-term) (AP17819PU-N) in Ramos, NCI-H460 cell line and mouse brain tissue lysates (35ug/lane). UCHL1 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of UCHL1 (arrow) using rabbit polyclonal UCHL1 Antibody (C-term) (AP17819PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the UCHL1 gene (Lane 2) .
