abx011403

antibody from Abbexa

Targeting: PRTN3 ACPA, AGP7, C-ANCA, MBT, P29, PR-3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

abx011403

Provider

Abbexa

Product name

Proteinase 3 Antibody

Antibody type

Monoclonal

Description

Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.