Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- H00005209-D01P - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#H00005209-D01P, RRID:AB_1578644
- Product name
- PFKFB3 purified MaxPab rabbit polyclonal antibody (D01P)
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against a full-length human PFKFB3 protein.
- Antigen sequence
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSP
TVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFN
VGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALA
ALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHF
AKENDFKAFFIESVCDDPTVVASNIMEVKISSPDY
KDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDL
SLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQ
PRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFAS
ALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPY
EQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQ
DKYYYRYPTGESYQDLVQRLEPVIMELERQENVLV
ICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNP
LMRRNSVTPLASPEPTKKPRINSFEEHVASTSAAL
PSCLPPEVPTQLPGQNMKGSRSSADSSRKH- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Submitted references Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway.
Yamamoto T, Takano N, Ishiwata K, Ohmura M, Nagahata Y, Matsuura T, Kamata A, Sakamoto K, Nakanishi T, Kubo A, Hishiki T, Suematsu M
Nature communications 2014 Mar 17;5:3480
Nature communications 2014 Mar 17;5:3480
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western Blot analysis of PFKFB3 expression in transfected 293T cell line (H00005209-T01) by PFKFB3 MaxPab polyclonal antibody.Lane 1: PFKFB3 transfected lysate(59.60 KDa).Lane 2: Non-transfected lysate.
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- PFKFB3 MaxPab rabbit polyclonal antibody. Western Blot analysis of PFKFB3 expression in human kidney.