Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 11250-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11250-1-AP, RRID:AB_2269906
- Product name
- S100A10 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated S100A10 antibody (Cat. #11250-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
The thrombin receptor modulates astroglia-neuron trophic coupling and neural repair after spinal cord injury.
5α-Epoxyalantolactone Inhibits Metastasis of Triple-Negative Breast Cancer Cells by Covalently Binding a Conserved Cysteine of Annexin A2.
Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury.
Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche.
Matrine treatment induced an A2 astrocyte phenotype and protected the blood-brain barrier in CNS autoimmunity.
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Differential and paradoxical roles of new-generation antidepressants in primary astrocytic inflammation.
The effects of A1/A2 astrocytes on oligodendrocyte linage cells against white matter injury under prolonged cerebral hypoperfusion.
Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.
Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain.
S100A10 Has a Critical Regulatory Function in Mammary Tumor Growth and Metastasis: Insights Using MMTV-PyMT Oncomice and Clinical Patient Sample Analysis.
Proteomic analysis of human periodontal ligament cells under hypoxia.
Down-regulation effects of IFN-α on p11, 5-htr1b and 5-HTR4 protein levels were affected by NH4CL or MG132 treatment in SH-sy5y cells.
S100A10, a novel biomarker in pancreatic ductal adenocarcinoma.
Probable involvement of p11 with interferon alpha induced depression.
Label-free quantification proteomics reveals novel calcium binding proteins in matrix vesicles isolated from mineralizing Saos-2 cells.
Feedback regulation of endothelial cell surface plasmin generation by PKC-dependent phosphorylation of annexin A2.
Liu C, Shen L, Xu L, Zhu A, Huang Y
Cellular signalling 2022 Jan;89:110183
Cellular signalling 2022 Jan;89:110183
The thrombin receptor modulates astroglia-neuron trophic coupling and neural repair after spinal cord injury.
Kim HN, Triplet EM, Radulovic M, Bouchal S, Kleppe LS, Simon WL, Yoon H, Scarisbrick IA
Glia 2021 Sep;69(9):2111-2132
Glia 2021 Sep;69(9):2111-2132
5α-Epoxyalantolactone Inhibits Metastasis of Triple-Negative Breast Cancer Cells by Covalently Binding a Conserved Cysteine of Annexin A2.
Wei M, Zhou Y, Li C, Yang Y, Liu T, Liu Y, Wei Y, Liu N, Liu S, Wang Q, Cao S, Sun Y, Sheng P, Lu C, Yang C, Liu X, Yang G
Journal of medicinal chemistry 2021 Sep 9;64(17):12537-12547
Journal of medicinal chemistry 2021 Sep 9;64(17):12537-12547
Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury.
Zhai X, Chen K, Yang H, Li B, Zhou T, Wang H, Zhou H, Chen S, Zhou X, Wei X, Bai Y, Li M
Journal of nanobiotechnology 2021 Sep 8;19(1):274
Journal of nanobiotechnology 2021 Sep 8;19(1):274
Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche.
He X, Smith SE, Chen S, Li H, Wu D, Meneses-Giles PI, Wang Y, Hembree M, Yi K, Zhao X, Guo F, Unruh JR, Maddera LE, Yu Z, Scott A, Perera A, Wang Y, Zhao C, Bae K, Box A, Haug JS, Tao F, Hu D, Hansen DM, Qian P, Saha S, Dixon D, Anant S, Zhang D, Lin EH, Sun W, Wiedemann LM, Li L
Cell reports 2021 Sep 7;36(10):109674
Cell reports 2021 Sep 7;36(10):109674
Matrine treatment induced an A2 astrocyte phenotype and protected the blood-brain barrier in CNS autoimmunity.
Jing Y, Ma R, Chu Y, Dou M, Wang M, Li X, Zhu L
Journal of chemical neuroanatomy 2021 Nov;117:102004
Journal of chemical neuroanatomy 2021 Nov;117:102004
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Qu H, Gong X, Liu X, Zhang R, Wang Y, Huang B, Zhang L, Zheng H, Zheng Y
Diabetes 2021 Jun;70(6):1372-1387
Diabetes 2021 Jun;70(6):1372-1387
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Shao L, Jiang GT, Yang XL, Zeng ML, Cheng JJ, Kong S, Dong X, Chen TX, Han S, Yin J, Liu WH, He XH, He C, Peng BW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
Differential and paradoxical roles of new-generation antidepressants in primary astrocytic inflammation.
He JH, Liu RP, Peng YM, Guo Q, Zhu LB, Lian YZ, Hu BL, Fan HH, Zhang X, Zhu JH
Journal of neuroinflammation 2021 Feb 18;18(1):47
Journal of neuroinflammation 2021 Feb 18;18(1):47
The effects of A1/A2 astrocytes on oligodendrocyte linage cells against white matter injury under prolonged cerebral hypoperfusion.
Miyamoto N, Magami S, Inaba T, Ueno Y, Hira K, Kijima C, Nakajima S, Yamashiro K, Urabe T, Hattori N
Glia 2020 Sep;68(9):1910-1924
Glia 2020 Sep;68(9):1910-1924
Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.
Lou Y, Han M, Liu H, Niu Y, Liang Y, Guo J, Zhang W, Wang H
Cellular & molecular immunology 2020 Oct;17(10):1053-1062
Cellular & molecular immunology 2020 Oct;17(10):1053-1062
Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain.
Yoon H, Choi CI, Triplet EM, Langley MR, Kleppe LS, Kim HN, Simon WL, Scarisbrick IA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Feb 12;40(7):1483-1500
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Feb 12;40(7):1483-1500
S100A10 Has a Critical Regulatory Function in Mammary Tumor Growth and Metastasis: Insights Using MMTV-PyMT Oncomice and Clinical Patient Sample Analysis.
Bharadwaj AG, Dahn ML, Liu RZ, Colp P, Thomas LN, Holloway RW, Marignani PA, Too CK, Barnes PJ, Godbout R, Marcato P, Waisman DM
Cancers 2020 Dec 7;12(12)
Cancers 2020 Dec 7;12(12)
Proteomic analysis of human periodontal ligament cells under hypoxia.
Li Q, Luo T, Lu W, Yi X, Zhao Z, Liu J
Proteome science 2019;17:3
Proteome science 2019;17:3
Down-regulation effects of IFN-α on p11, 5-htr1b and 5-HTR4 protein levels were affected by NH4CL or MG132 treatment in SH-sy5y cells.
Guo J, Ding H, Lv Z, Jiao J, Wang H, Ji Y
Journal of biosciences 2019 Sep;44(4)
Journal of biosciences 2019 Sep;44(4)
S100A10, a novel biomarker in pancreatic ductal adenocarcinoma.
Bydoun M, Sterea A, Liptay H, Uzans A, Huang WY, Rodrigues GJ, Weaver ICG, Gu H, Waisman DM
Molecular oncology 2018 Nov;12(11):1895-1916
Molecular oncology 2018 Nov;12(11):1895-1916
Probable involvement of p11 with interferon alpha induced depression.
Guo J, Zhang W, Zhang L, Ding H, Zhang J, Song C, Zhang Y, Xia N, Li M, Liang Y, Hu X, Luan H, Wang H
Scientific reports 2016 Jan 29;6:17029
Scientific reports 2016 Jan 29;6:17029
Label-free quantification proteomics reveals novel calcium binding proteins in matrix vesicles isolated from mineralizing Saos-2 cells.
Zhou X, Cui Y, Luan J, Zhou X, Zhang G, Zhang X, Han J
Bioscience trends 2013 Jun;7(3):144-51
Bioscience trends 2013 Jun;7(3):144-51
Feedback regulation of endothelial cell surface plasmin generation by PKC-dependent phosphorylation of annexin A2.
He KL, Sui G, Xiong H, Broekman MJ, Huang B, Marcus AJ, Hajjar KA
The Journal of biological chemistry 2011 Apr 29;286(17):15428-39
The Journal of biological chemistry 2011 Apr 29;286(17):15428-39
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 11250-1-AP(S100A10 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using S100A10 antibody 11250-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 11250-1-AP(S100A10 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The S100A10 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human S100A10. This antibody recognizes human,mouse,rat antigen. The S100A10 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.