Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 14173-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14173-1-AP, RRID:AB_2080046
- Product name
- CHD4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CHD4 antibody (Cat. #14173-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis.
ZNF410Â Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
CHD4 Promotes Breast Cancer Progression as a Coactivator of Hypoxia-Inducible Factors.
CHD4/NuRD complex regulates complement gene expression and correlates with CD8 T cell infiltration in human hepatocellular carcinoma.
Runx1 repression by histone deacetylation is critical for Setbp1-induced mouse myeloid leukemia development.
Vecellio M, Chen L, Cohen CJ, Cortes A, Li Y, Bonham S, Selmi C, Brown MA, Fischer R, Knight JC, Wordsworth BP
Arthritis & rheumatology (Hoboken, N.J.) 2021 Jun;73(6):980-990
Arthritis & rheumatology (Hoboken, N.J.) 2021 Jun;73(6):980-990
ZNF410Â Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Lan X, Ren R, Feng R, Ly LC, Lan Y, Zhang Z, Aboreden N, Qin K, Horton JR, Grevet JD, Mayuranathan T, Abdulmalik O, Keller CA, Giardine B, Hardison RC, Crossley M, Weiss MJ, Cheng X, Shi J, Blobel GA
Molecular cell 2021 Jan 21;81(2):239-254.e8
Molecular cell 2021 Jan 21;81(2):239-254.e8
CHD4 Promotes Breast Cancer Progression as a Coactivator of Hypoxia-Inducible Factors.
Wang Y, Chen Y, Bao L, Zhang B, Wang JE, Kumar A, Xing C, Wang Y, Luo W
Cancer research 2020 Sep 15;80(18):3880-3891
Cancer research 2020 Sep 15;80(18):3880-3891
CHD4/NuRD complex regulates complement gene expression and correlates with CD8 T cell infiltration in human hepatocellular carcinoma.
Shao S, Cao H, Wang Z, Zhou D, Wu C, Wang S, Xia D, Zhang D
Clinical epigenetics 2020 Feb 18;12(1):31
Clinical epigenetics 2020 Feb 18;12(1):31
Runx1 repression by histone deacetylation is critical for Setbp1-induced mouse myeloid leukemia development.
Vishwakarma BA, Nguyen N, Makishima H, Hosono N, Gudmundsson KO, Negi V, Oakley K, Han Y, Przychodzen B, Maciejewski JP, Du Y
Leukemia 2016 Jan;30(1):200-8
Leukemia 2016 Jan;30(1):200-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14173-1-AP(CHD4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A549 cells, using CHD4 antibody 14173-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 14173-1-AP(CHD4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue