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- References [5]
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- Product number
- ABIN151937 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 1-50), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term, AA 1-50
- Vial size
- 0.1 mL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons.
Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease.
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation.
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe.
Amadoro G, Corsetti V, Florenzano F, Atlante A, Ciotti MT, Mongiardi MP, Bussani R, Nicolin V, Nori SL, Campanella M, Calissano P
Neurobiology of disease 2014 Feb;62:489-507
Neurobiology of disease 2014 Feb;62:489-507
Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease.
Yasuda T, Hayakawa H, Nihira T, Ren YR, Nakata Y, Nagai M, Hattori N, Miyake K, Takada M, Shimada T, Mizuno Y, Mochizuki H
Journal of neuropathology and experimental neurology 2011 Aug;70(8):686-97
Journal of neuropathology and experimental neurology 2011 Aug;70(8):686-97
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation.
Lutz AK, Exner N, Fett ME, Schlehe JS, Kloos K, Lämmermann K, Brunner B, Kurz-Drexler A, Vogel F, Reichert AS, Bouman L, Vogt-Weisenhorn D, Wurst W, Tatzelt J, Haass C, Winklhofer KF
The Journal of biological chemistry 2009 Aug 21;284(34):22938-51
The Journal of biological chemistry 2009 Aug 21;284(34):22938-51
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Exner N, Treske B, Paquet D, Holmström K, Schiesling C, Gispert S, Carballo-Carbajal I, Berg D, Hoepken HH, Gasser T, Krüger R, Winklhofer KF, Vogel F, Reichert AS, Auburger G, Kahle PJ, Schmid B, Haass C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Nov 7;27(45):12413-8
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Nov 7;27(45):12413-8
Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe.
Meijer M, Karimi-Busheri F, Huang TY, Weinfeld M, Young D
The Journal of biological chemistry 2002 Feb 8;277(6):4050-5
The Journal of biological chemistry 2002 Feb 8;277(6):4050-5
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