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- Product number
- ABIN152067 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 258-274) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 258-274
- Vial size
- 0.1 mg
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation.
The kinase domain of mitochondrial PINK1 faces the cytoplasm.
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.
Xiong H, Wang D, Chen L, Choo YS, Ma H, Tang C, Xia K, Jiang W, Ronai Z, Zhuang X, Zhang Z
The Journal of clinical investigation 2009 Mar;119(3):650-60
The Journal of clinical investigation 2009 Mar;119(3):650-60
The kinase domain of mitochondrial PINK1 faces the cytoplasm.
Zhou C, Huang Y, Shao Y, May J, Prou D, Perier C, Dauer W, Schon EA, Przedborski S
Proceedings of the National Academy of Sciences of the United States of America 2008 Aug 19;105(33):12022-7
Proceedings of the National Academy of Sciences of the United States of America 2008 Aug 19;105(33):12022-7
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.
Sim CH, Lio DS, Mok SS, Masters CL, Hill AF, Culvenor JG, Cheng HC
Human molecular genetics 2006 Nov 1;15(21):3251-62
Human molecular genetics 2006 Nov 1;15(21):3251-62
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- Experimental details
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- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
