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- Antibody Data
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- References [2]
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- Western blot [2]
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- Product number
- NB100-2866 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-2866, RRID:AB_10003040
- Product name
- Rabbit Polyclonal TPR Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer.
Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis.
Wu L, Zhou B, Oshiro-Rapley N, Li M, Paulo JA, Webster CM, Mou F, Kacergis MC, Talkowski ME, Carr CE, Gygi SP, Zheng B, Soukas AA
Cell 2016 Dec 15;167(7):1705-1718.e13
Cell 2016 Dec 15;167(7):1705-1718.e13
Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis.
Schweizer N, Ferrás C, Kern DM, Logarinho E, Cheeseman IM, Maiato H
The Journal of cell biology 2013 Dec 23;203(6):883-93
The Journal of cell biology 2013 Dec 23;203(6):883-93
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Enhanced validation
- Submitted by
- Novus Biologicals (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Knockout Validated: TPR Antibody [NB100-2866] - Lane 1 contians wildtype MDA-MB-231 cell lysate nuclear extract. Lanes 2, 3 and 4 contain the TPR knocked down MDA-MB-231 cell lysate nuclear extract. The lowered intensity of the bands in knocked down cell lines compared to wildtype supports antibody specificity to intended target protein. This image was submitted by customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TPR Antibody [NB100-2866] - Detection of Human TPR on HeLa whole cell lysate using NB100-2866. TPR was also immunoprecipitated by rabbit anti-TPR antibodies NB100-2864, NB100-2865 and NB100-2867.
