Tissue expression
Cell line expression
Protein structure
UBN1
Ubinuclein 1Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3. [provided by RefSeq, Oct 2016]
Top validated antibodies |
|||||
Proteintech Group | ![]() |
1 references | Polyclonal |
|
|
LSBio | ![]() |
Polyclonal |
|
||
Invitrogen Antibodies | ![]() |
Monoclonal |
|
||
GeneTex | ![]() |
Polyclonal |
|
||
Novus Biologicals | ![]() |
1 references | Polyclonal |
|