Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11065-3-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11065-3-AP, RRID:AB_2123101
- Product name
- IGFBP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IGFBP2 antibody (Cat. #11065-3-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Deciphering m6A signatures in hepatocellular carcinoma: Single-cell insights, immune landscape, and the protective role of IGFBP3.
Comprehensive analysis of m6A RNA methylation modification patterns and the immune microenvironment in osteoarthritis.
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
SARM1 promotes the neuroinflammation and demyelination through IGFBP2/NF-κB pathway in experimental autoimmune encephalomyelitis mice.
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis.
The cuproptosis-related signature associated with the tumor environment and prognosis of patients with glioma.
Exosomes from cisplatin-induced dormant cancer cells facilitate the formation of premetastatic niche in bone marrow through activating glycolysis of BMSCs.
IGFBP2 function as a novel biomarker for active lupus nephritis.
HMGA2 contributes to vascular development and sprouting angiogenesis by promoting IGFBP2 production.
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
The proteomic profiling of multiple tissue damage in chickens for a selenium deficiency biomarker discovery.
IGF1 Knockdown Hinders Myocardial Development through Energy Metabolism Dysfunction Caused by ROS-Dependent FOXO Activation in the Chicken Heart.
MiR-34b-5p Mediates the Proliferation and Differentiation of Myoblasts by Targeting IGFBP2.
Selenium deficiency-induced thioredoxin suppression and thioredoxin knock down disbalanced insulin responsiveness in chicken cardiomyocytes through PI3K/Akt pathway inhibition.
Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.
Chen S, Liu J, Zhang S, Zhao L, Zhang J, Han P, Zhang Q, Liu Y, Wang F, Li J
Environmental toxicology 2024 Feb 16;
Environmental toxicology 2024 Feb 16;
Comprehensive analysis of m6A RNA methylation modification patterns and the immune microenvironment in osteoarthritis.
Liu Z, Liu H, Li D, Ma L, Lu T, Sun H, Zhang Y, Yang H
Frontiers in immunology 2023;14:1128459
Frontiers in immunology 2023;14:1128459
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
You B, Zhang T, Zhang W, Pei Y, Huang D, Lei Y, Zhang S, Qiu C, Zhang J, Gu Z, Cheng L, Chen J
iScience 2023 Mar 17;26(3):106151
iScience 2023 Mar 17;26(3):106151
SARM1 promotes the neuroinflammation and demyelination through IGFBP2/NF-κB pathway in experimental autoimmune encephalomyelitis mice.
Zhang J, Jin L, Hua X, Wang M, Wang J, Xu X, Liu H, Qiu H, Sun H, Dong T, Yang D, Zhang X, Wang Y, Huang Z
Acta physiologica (Oxford, England) 2023 Jun;238(2):e13974
Acta physiologica (Oxford, England) 2023 Jun;238(2):e13974
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis.
Chen L, Zhong XL, Cao WY, Mao ML, Liu DD, Liu WJ, Zu XY, Liu JH
European journal of pharmacology 2023 Dec 5;960:176122
European journal of pharmacology 2023 Dec 5;960:176122
The cuproptosis-related signature associated with the tumor environment and prognosis of patients with glioma.
Wang W, Lu Z, Wang M, Liu Z, Wu B, Yang C, Huan H, Gong P
Frontiers in immunology 2022;13:998236
Frontiers in immunology 2022;13:998236
Exosomes from cisplatin-induced dormant cancer cells facilitate the formation of premetastatic niche in bone marrow through activating glycolysis of BMSCs.
Xu J, Feng X, Yin N, Wang L, Xie Y, Gao Y, Xiang J
Frontiers in oncology 2022;12:922465
Frontiers in oncology 2022;12:922465
IGFBP2 function as a novel biomarker for active lupus nephritis.
Li H, Liang J, Gao Y, Liu M, Xia N, Kong W, Zheng L, Zhang Y, Li Z, Chen H, Liu S, Sun L
Journal of molecular medicine (Berlin, Germany) 2022 Oct;100(10):1479-1491
Journal of molecular medicine (Berlin, Germany) 2022 Oct;100(10):1479-1491
HMGA2 contributes to vascular development and sprouting angiogenesis by promoting IGFBP2 production.
Wang J, Chen Y, Zeng Z, Feng R, Wang Q, Zhang Q, Sun K, Chen AF, Lu Y, Yu Y
Experimental cell research 2021 Nov 1;408(1):112831
Experimental cell research 2021 Nov 1;408(1):112831
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
Tan X, Shi L, Banerjee P, Liu X, Guo HF, Yu J, Bota-Rabassedas N, Rodriguez BL, Gibbons DL, Russell WK, Creighton CJ, Kurie JM
The Journal of clinical investigation 2021 Jan 4;131(1)
The Journal of clinical investigation 2021 Jan 4;131(1)
The proteomic profiling of multiple tissue damage in chickens for a selenium deficiency biomarker discovery.
Zhang Z, Liu Q, Yang J, Yao H, Fan R, Cao C, Liu C, Zhang S, Lei X, Xu S
Food & function 2020 Feb 26;11(2):1312-1321
Food & function 2020 Feb 26;11(2):1312-1321
IGF1 Knockdown Hinders Myocardial Development through Energy Metabolism Dysfunction Caused by ROS-Dependent FOXO Activation in the Chicken Heart.
Gong Y, Yang J, Liu Q, Cai J, Zheng Y, Zhang Y, Yu D, Liu H, Zhang Z
Oxidative medicine and cellular longevity 2019;2019:7838754
Oxidative medicine and cellular longevity 2019;2019:7838754
MiR-34b-5p Mediates the Proliferation and Differentiation of Myoblasts by Targeting IGFBP2.
Wang Z, Zhang X, Li Z, Abdalla BA, Chen Y, Nie Q
Cells 2019 Apr 17;8(4)
Cells 2019 Apr 17;8(4)
Selenium deficiency-induced thioredoxin suppression and thioredoxin knock down disbalanced insulin responsiveness in chicken cardiomyocytes through PI3K/Akt pathway inhibition.
Yang J, Hamid S, Cai J, Liu Q, Xu S, Zhang Z
Cellular signalling 2017 Oct;38:192-200
Cellular signalling 2017 Oct;38:192-200
Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.
Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, Cebotaru V, Chiaravalli M, Boletta A, Piontek K, Germino GG, Weinman EJ, Watnick T, Qian F
Nature communications 2014 Nov 18;5:5482
Nature communications 2014 Nov 18;5:5482
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 11065-3-AP(IGFBP2 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IGFBP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IGFBP2. This antibody recognizes human, mouse, rat antigen. The IGFBP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.