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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- 676002 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#676002, RRID:AB_2565609
- Product name
- PURE anti-TIMP-1
- Antibody type
- Monoclonal
- Antigen
- Recombinant human TIMP-1.
- Description
- TIMP-1 (Tissue inhibitor of metalloproteinase 1) is a glycoprotein that is well recognized for its role in extracellular matrix remodeling through controlling the activity of matrix metalloproteinases (MMPs). Independent of MMP inhibition, TIMPs also act as signaling molecules and plays important roles in cell growth, apoptosis, differentiation, angiogenesis, and oncogenesis. High level of TIMP-1 protein has been found in several types of cancers and associated with a poor patient prognosis. TIMP-1 may be useful as a cancer prognostic marker in combination with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1).
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- M2004D03
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Western blot analysis of 50ng recombinant human TIMP-1 (lane 1, Cat. No. 592402), and recombinant mouse TIMP-1 (lane 2, Cat. No. 593702) using anti-TIMP-1 antibody (clone M2004D03) and HRP anti-mouse IgG antibody (Cat. No. 405306).
- Conjugate
- Unconjugated
