AFC-219CL

antibody from Creative Biolabs

Targeting: EMP2 XMP

No application information provided.

Antibody Data

Product number

AFC-219CL

Provider

Creative Biolabs

Product name

Afuco? Anti-Human EMP2 ADCC Recombinant Antibody (PG-101), ADCC Enhanced

Antibody type

Monoclonal

Description

Anti-EMP2 ADCC Enhanced Antibody (PG-101) is an ADCC enhanced antibody produced by our Afuco? platform. This is a novel IgG1 monoclonal antibody to EMP2, PG-101 treatment in the primary tumor is sufficient to reduce secondary tumor formation in triple negative breast cancer cells on the order of 1:20, 000 compared to the control treated mice. PG-101 in combination with docetaxel can cure up to 80% of animals treated. This effect is lasting as these mice have shown no rebound in tumor load more than 2 months following the last treatment. Collectively, these results show that PG-101 therapy has the potential to revolutionize the outcomes for women with breast cancer.

Reactivity

Human

Storage

Store at ¨C20 or -70¡ãC upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.