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Cell line expression
Protein structure
RNF216
Ring finger protein 216TRIAD3, UBCE7IP1, ZIN
This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-20079 |
2 references | Polyclonal |
WB
ICC
IHC
OA
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| antibodies-online | ABIN501040 |
4 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | NBP1-76592 |
Polyclonal |
WB
EL
ICC
IHC
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| Boster Biological Technology | A05841 |
Polyclonal |
WB
EL
ICC
IHC
|
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| Abnova Corporation | PAB12931 |
3 references | Polyclonal |
WB
IHC
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