BS6188

antibody from Bioworld Technology, Inc
Targeting: TICAM1 MGC35334, PRVTIRB, TICAM-1, TRIF
Provider product page for BS6188
Western blot
Immunohistochemistry

Antibody data

Product number
BS6188 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TICAM1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TICAM1.
Description
Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TICAM1 protein structure - BS6188 shown in red.