BS8211

antibody from Bioworld Technology, Inc
Targeting: RNGTT hCAP, HCE, HCE1
Provider product page for BS8211
Western blot
Immunohistochemistry

Antibody data

Product number
BS8211 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RNGTT polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human RNGTT.
Description
RNGTT (RNA guanylyltransferase and 5'-phosphatase), also known as HCE, HCE1, hCAP or CAP1A, is a 597 amino acid protein that localizes to the nucleus and exists as four alternatively spliced isoforms. Expressed in kidney, lung, heart, brain, liver, testis, skin and muscle, RNGTT acts as a bifunctional mRNA-capping enzyme that exhibits RNA 5'-triphosphatase activity at its N-terminus and mRNA guanylyltransferase activity at its C-terminus. Via its catalytic activity, RNGTT facilitates the first two steps of mRNA cap formation, naming the removal of a ÎÛ-phosphate from the end of nascent mRNA and the subsequent transfer of the phospho residue to the 5£ª-diphosphate terminus. The gene encoding RNGTT maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RNGTT protein structure - BS8211 shown in red.